Jose Reyes
@josei.reyesdhlhs4o8kh• Jun 28, 2022
Efficient establishment of reactivatable latency by an acyclovir-resistant herpes simplex virus 1 thymidine kinase substitution mutant with reduced neuronal replication - ScienceDirect
The first-line drug for HSV-1 infection is acyclovir (ACV), which is a guanine analogue that inhibits HSV replication at the level of viral DNA synthesis
However ACV cannot eliminate latent virus, which can reactivate to cause recurrent diseases even in the face of ACV treatment.
ACVr is common in immunocompromised patients, but rare in immunocompetent patients
Efficient establishment of reactivatable latency by an acyclovir-resistant herpes simplex virus 1 thymidine kinase substitution mutant with reduced neuronal replication - ScienceDirectwww.sciencedirect.com
Jose Reyes
@josei.reyesdhlhs4o8kh• Jun 28, 2022
Frontiers | Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man | Immunology
chromatinized episomes,
The mechanisms specifying the contrasting fates of HSV-1 in neurons and epithelial cells may include differential genome silencing and chromatinization, dictated by variation in access of immune modulating viral tegument proteins to the cell body, and protection of neurons by autophagy.
Frontiers | Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man | Immunologywww.frontiersin.org
Jose Reyes
@josei.reyesdhlhs4o8kh• May 28, 2022
Study Quiz 2 (página 1 de 5)
reduced pulsatile flow compared to the veins of the contralateral side
Study Quiz 2 (página 1 de 5)miscursos.uag.mx
Jose Reyes
@josei.reyesdhlhs4o8kh• May 25, 2022
Frontiers | Pompe disease: from pathophysiology to therapy and back again | Aging Neuroscience
(ERT) proved to be successful in reversing cardiac but not skeletal muscle abnormalities.
Pompe disease is a lysosomal storage disorder in which acid alpha-glucosidase (GAA) is deficient or absent.
Deficiency of this lysosomal enzyme results in progressive expansion of glycogen-filled lysosomes in multiple tissues, with cardiac and skeletal muscle being the most severely affected.
Frontiers | Pompe disease: from pathophysiology to therapy and back again | Aging Neurosciencewww.frontiersin.org
Jose Reyes
@josei.reyesdhlhs4o8kh• May 23, 2022
Popliteal fossa: Anatomy and contents | Kenhub
These include the two terminal branches of the sciatic nerve, the popliteal vessels and short saphenous vein.
Popliteal fossa: Anatomy and contents | Kenhubwww.kenhub.com
Jose Reyes
@josei.reyesdhlhs4o8kh• May 20, 2022
Gluteal muscles: Attachments, supply and function | Kenhub
In terms of function, the gluteal muscles act on the hip joint,
facilitate abduction and extension of the thigh but some also assist in the adduction, external rotation and internal rotation of the thigh
gluteal (buttock) region
Gluteal muscles: Attachments, supply and function | Kenhubwww.kenhub.com
Jose Reyes
@josei.reyesdhlhs4o8kh• May 15, 2022
Review - Assessment | Review - Assessment | PHYS Courseware | Harvard Medical School
resistance of the systemic circulation of the cardiovascular system has decreased significantly.
, in whom the resistance of the systemic circulation of the cardiovascular system decreases significantly.
Review - Assessment | Review - Assessment | PHYS Courseware | Harvard Medical Schoolonlinelearning.hms.harvard.edu
Jose Reyes
@josei.reyesdhlhs4o8kh• May 15, 2022
Quiz Yourself | Key Concepts | PHYS Courseware | Harvard Medical School
Compare the effect of a 50% airway narrowing in the trachea versus a 50% narrowing in one of the smaller airways.
Thus, the gas with the lowest density is most likely to be associated with laminar flow. The mixture of helium and oxygen provides the lowest density gas.
Quiz Yourself | Key Concepts | PHYS Courseware | Harvard Medical Schoolonlinelearning.hms.harvard.edu
Jose Reyes
@josei.reyesdhlhs4o8kh• May 14, 2022
Review - Assessment | Review - Assessment | PHYS Courseware | Harvard Medical School
As such, his heart doesn’t pump blood well, and he has expanded blood volume and elevated venous pressures.
45g of a product that equally distributes into all 3 compartments of the body
Review - Assessment | Review - Assessment | PHYS Courseware | Harvard Medical Schoolonlinelearning.hms.harvard.edu
Jose Reyes
@josei.reyesdhlhs4o8kh• May 9, 2022
Neurocutaneous syndromes - AMBOSS
With the exception of Sturge-Weber syndrome, which is caused by a noninherited developmental anomaly of neural crest derivatives, and ataxia telangiectasia, which follows an autosomal recessive inheritance pattern, neurocutaneous syndromes disorders follow an autosomal dominant inheritance pattern, although spontaneous mutations are also possible
With the exception of Sturge-Weber syndrome, which is caused by a noninherited developmental anomaly of neural crest derivatives, and ataxia telangiectasia, which follows an autosomal recessive inheritance pattern, neurocutaneous syndromes disorders follow an autosomal dominant inheritance pattern, although spontaneous mutations are also possible
Neurocutaneous syndromes - AMBOSSnext.amboss.com